![]() ![]() The tables describe the key clinical features and recommended tests to help accurately diagnose generalized rashes. In part I of this two-part article, tables listing common, uncommon, and rare causes of generalized rash are presented to help generate an inclusive differential diagnosis. When a specific diagnosis is not immediately apparent, it is important to generate an inclusive differential diagnosis to guide diagnostic strategy and initial treatment. A rapid and accurate diagnosis is critically important to make treatment decisions, especially when mortality or significant morbidity can occur without prompt intervention. Any duplication or distribution of the information contained herein is strictly prohibited.Physicians often have difficulty diagnosing a generalized rash because many different conditions produce similar rashes, and a single condition can result in different rashes with varied appearances. Links to other sites are provided for information only - they do not constitute endorsements of those other sites. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. ![]() This site complied with the HONcode standard for trustworthy health information from 1995 to 2022, after which HON (Health On the Net, a not-for-profit organization that promoted transparent and reliable health information online) was discontinued. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. is among the first to achieve this important distinction for online health information and services. follows rigorous standards of quality and accountability. is accredited by URAC, for Health Content Provider (URAC's accreditation program is an independent audit to verify that A.D.A.M. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Vorvick, MD, Clinical Professor, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Philadelphia, PA: Elsevier 2020:chap 162. Approach to the patient with bleeding and thrombosis. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. The acutely ill patient with fever and rash. Philadelphia, PA: Elsevier 2023:chap 126. Hematology: Basic Principles and Practice. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Evaluation of the patient with suspected bleeding disorders.
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